Excess Folic Acid During Fertility Treatment May Increase Chances of Twins

A recent British study has found a potential link between increased folic acid intake during fertility treatment and a higher chance of having twins when more than one embryo is transferred. Folic acid, a B vitamin known for its protective effects against birth defects, has been a key recommendation for women during pregnancy for decades. Since 1992, the U.S. Department of Health has recommended folic acid supplements to help prevent neural tube defects like spina bifida, leading to a 32% reduction in such cases, according to the Centers for Disease Control and Prevention (CDC).

The Study on Folic Acid and Fertility Treatment

Research conducted by Paul Haggarty at the University of Aberdeen studied the folate levels in the blood of 602 women undergoing fertility treatment. The results revealed that women with higher blood concentrations of folate had an increased likelihood of twin births when multiple embryos were transferred. However, the study also found that folate levels did not influence the overall chances of getting pregnant.

At San Diego Fertility Center, Drs. Hummel and Kettel prescribe folic acid supplements as part of a comprehensive fertility care plan to ensure the health of both mother and baby. Folic acid is essential for its role in protecting against birth defects, but patients should take care to follow their doctor’s recommendations and avoid using additional folic acid supplements beyond prescribed prenatal vitamins and folic acid.

Understanding Folic Acid’s Role in Pregnancy and Fertility

Folic acid is a crucial nutrient for women trying to conceive and during early pregnancy. It helps prevent neural tube defects and supports healthy fetal development. For women undergoing fertility treatments like IVF, ensuring the right amount of folic acid is part of a healthy fertility plan. However, as this new research suggests, it’s important to balance intake, especially for those undergoing treatments where more than one embryo is transferred.

Should You Be Concerned?

While the study indicates an increased chance of twins with higher folate levels, it’s important to remember that the benefits of folic acid—particularly in preventing birth defects—far outweigh potential risks. Still, it’s crucial to follow your fertility specialist’s guidance regarding supplement use. Drs. Hummel and Kettel emphasize the importance of sticking to prescribed supplements and avoiding additional over-the-counter folic acid products.

A Vital Supplement

Folic acid remains a vital part of fertility treatment and pregnancy care due to its role in preventing birth defects. While there is emerging evidence that higher folic acid intake may slightly increase the chance of twins when multiple embryos are transferred during IVF, the overall impact on pregnancy success remains unchanged. As always, consult your fertility specialist before making any changes to your supplement regimen.

For more information on folic acid’s role in fertility treatment and how San Diego Fertility Center can support you on your journey to parenthood, schedule a consultation with our expert team today.