What is preimplantation genetic testing (PGT)?
PGT involves running multiple tests on each embryo before implantation. This helps to increase the chances of a healthy pregnancy by reducing the risk of implanting an embryo with genetic or chromosomal abnormalities. This process can also decrease chances of miscarriage, which is often associated with chromosomal issues in the embryo.
How PGT treatment works
After your embryos grow for 5-6 days in our lab, our embryologists will biopsy your embryos and send the sample to a PGT lab, to run one or more of the following tests:
- PGT-A (Preimplantation Genetic Testing for Aneuploidy): This chromosomal test will help to decrease the chances of implantation issues or miscarriage, and can help detect chromosomal abnormalities. With this test it’s also possible to determine the sex of the embryo if you carry a genetic risk of sex-linked disease, or for other personal reasons.
- PGT-M (Preimplantation Genetic Testing for Monogenic Disorders): This genetic test is helpful for couples in which one or both partners are carriers of genetic mutations that could result in the baby having a monogenic disorder.
- PGT-SR (Preimplantation Genetic Testing for a Structural Rearrangement): This is a test that screens for structural issues in the chromosomes that form an abnormal embryo and will almost always result in miscarriage.
Is PGT right for me?
Whether you should pursue genetic testing is based on a number of factors including your age, genetic background, and medical history. Ultimately, PGT can improve the chances of pregnancy for anyone undergoing IVF. Knowing which embryos may result in miscarriage or abnormal pregnancy gives you more autonomy over your own experience and the health of your family.
PGT Success with San Diego Fertility Center
PGT is over 98% accurate in diagnosing chromosomal abnormalities.
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Paying for PGT
Though coverage for fertility care varies widely by insurance plan, the good news is that you have lots of options. We are committed to guiding you through your insurance benefits, out-of-pocket expenses, and other financing options every step of the way. With San Diego Fertility Center you will never be in the dark about cost.
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The majority of miscarriages are due to chromosomally abnormal embryos. A PGT-A test helps to identify a chromosomally normal embryo for implantation.
No, the biopsy for PGT does not harm the embryo. A very small number of cells are biopsied from an area that will eventually grow into the placenta. The inner cell mass, which is the part of the embryo that will become the baby, is not touched.
PGT-M is appropriate when a parent or a parent’s family member is a carrier of a genetic abnormality. This test can be done with PGT-A, and this information can be used to choose an embryo of a certain sex. Patients most often do this when they are the carrier of a sex-linked genetic disorder.